NUDCD1 Antikörper (AA 431-530) (Alexa Fluor 555)

Produktnummer ABIN6978553

Produktdetails anti-NUDCD1 Antikörper (Alexa Fluor 555)

Target: NUDCD1 (NudC Domain Containing 1 (NUDCD1))

Bindungsspezifität: AA 431-530

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUDCD1 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NUDCD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NUDCD1

Target: NUDCD1 (NudC Domain Containing 1 (NUDCD1))

Andere Bezeichnung: NUDCD1 (NUDCD1 Produkte)

Synonyme: Cml66 antikoerper, NUDCD1 antikoerper, CML66 antikoerper, OVA66 antikoerper, 4921532K09Rik antikoerper, AA407246 antikoerper, AW260430 antikoerper, AW556235 antikoerper, CML66-L antikoerper, RGD1310624 antikoerper, im:6901299 antikoerper, im:6912119 antikoerper, wu:fc11c02 antikoerper, zgc:110705 antikoerper, cml66 antikoerper, NudC domain containing 1 antikoerper, NudC domain-containing protein 1 antikoerper, NudC domain containing 1 S homeolog antikoerper, NUDCD1 antikoerper, nudcd1 antikoerper, CpipJ_CPIJ019282 antikoerper, nudc1 antikoerper, LOC777229 antikoerper, Nudcd1 antikoerper, nudcd1.S antikoerper

Hintergrund:

Synonyms: 4921532K09Rik, AA407246, AW260430, AW556235, Chronic myelogenous leukemia tumor antigen 66, CML66, CML66 L, FLJ14991, NudC domain containing 1, NudC domain-containing protein 1, NUDC1_HUMAN, nudcd1, OVA66, RGD1310624, Tumor antigen CML66.

Background: The NUDCD1 gene encodes the 583 amino acid CML66 protein which demonstrates expression in a variety of solid tumor cell lines and leukemias. Expression of CML66 in normal tissues is restricted to testis and heart. The CML66 antibody is found in sera of 18-38 % of patients with lung cancer, melanoma or prostate cancer. These findings indicate that CML66 may be immunogenic in a wide variety of malignancies and may be a target for antigen-specific immunotherapy. A short isoform of CML66, designated CML66-S, is a product of alternative splicing. CML66-S has the same C-terminus as full-lenghth CML66 (also designated CML66-L), but has a unique N-terminus. CML66-S shows predominant expression in testis, and is also expressed in very low levels in tumor cells, while CML66 is expressed in tumor cells and testis.

Gen-ID: 84955

UniProt: Q96RS6