LGI2 Antikörper (AA 201-300) (Alexa Fluor 555)

Produktnummer ABIN6978456

Produktdetails anti-LGI2 Antikörper (Alexa Fluor 555)

Target: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Bindungsspezifität: AA 201-300

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI2 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Sheep,Pig,Horse,Chicken,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LGI2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LGI2

Target: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Andere Bezeichnung: LGI2 (LGI2 Produkte)

Synonyme: LGIL2 antikoerper, mKIAA1916 antikoerper, leucine rich repeat LGI family member 2 antikoerper, leucine-rich repeat LGI family, member 2 antikoerper, leucine-rich repeat LGI family member 2 antikoerper, leucine-rich repeat LGI family, member 2a antikoerper, LGI2 antikoerper, Lgi2 antikoerper, lgi2 antikoerper, lgi2a antikoerper

Hintergrund:

Synonyms: KIAA1916, Leucine rich glioma inactivated protein 2, Leucine rich repeat LGI family member 2, Leucine-rich glioma-inactivated protein 2, Leucine-rich repeat LGI family member 2, LGI1 like protein 2, LGI1-like protein 2, LGI2, LGI2_HUMAN, LGIL2.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LGI2 (leucine-rich repeat LGI family, member 2), also known as KIAA1916 or LGIL2, is a 545 amino acid secreted protein that contains four LRR repeats and seven EAR repeats. Expressed in heart, brain and placenta, LGI2 shares high sequence similarity with other LGI family members and is thought to play a role in the pathogenesis of epileptic disorders.

Gen-ID: 55203

UniProt: Q8N0V4