DDX11 Antikörper (Alexa Fluor 350)

Produktnummer ABIN6977047

Produktdetails anti-DDX11 Antikörper (Alexa Fluor 350)

Target: DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX11 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KRG2/DDX11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DDX11

Target: DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))

Andere Bezeichnung: KRG2/DDX11 (DDX11 Produkte)

Synonyme: CHL1 antikoerper, CHLR1 antikoerper, KRG2 antikoerper, WABS antikoerper, 4732462I11Rik antikoerper, essa15a antikoerper, putative ATP-dependent RNA helicase DDX11-like protein 8 antikoerper, DEAD/H-box helicase 11 antikoerper, DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 antikoerper, LOC100448472 antikoerper, DDX11 antikoerper, Ddx11 antikoerper

Hintergrund:

Synonyms: CHL1, CHL1 related helicase gene 1, CHL1-like helicase homolog, CHL1-related protein 1, CHLR1, Ddx11, DDX11_HUMAN, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 11, DEAD/H box protein 11, hCHLR1, Keratinocyte growth factor regulated gene 2 protein, Keratinocyte growth factor-regulated gene 2 protein, KRG 2, KRG-2, KRG2, Probable ATP dependent RNA helicase DDX11, Probable ATP-dependent RNA helicase DDX11.

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Gen-ID: 1663

UniProt: Q96FC9

Pathways: ER-Nucleus Signaling