FERMT1 Antikörper (AA 601-677) (Alexa Fluor 350)

Produktnummer ABIN6976643

Produktdetails anti-FERMT1 Antikörper (Alexa Fluor 350)

Target: FERMT1 (Fermitin Family Member 1 (FERMT1))

Bindungsspezifität: AA 601-677

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FERMT1 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Kindlin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FERMT1

Target: FERMT1 (Fermitin Family Member 1 (FERMT1))

Andere Bezeichnung: Kindlin (FERMT1 Produkte)

Synonyme: C20orf42 antikoerper, DTGCU2 antikoerper, KIND1 antikoerper, UNC112A antikoerper, URP1 antikoerper, 5830467P10Rik antikoerper, Kindlin-1 antikoerper, RGD1306816 antikoerper, si:ch73-22c10.1 antikoerper, wu:fc32b07 antikoerper, fermitin family member 1 antikoerper, fermitin family member 1 S homeolog antikoerper, fermitin family homolog 1 antikoerper, FERMT1 antikoerper, Fermt1 antikoerper, fermt1.S antikoerper, fermt1 antikoerper, LOC100548276 antikoerper

Hintergrund:

Synonyms: C20orf42, Chromosome 20 open reading frame 42, DTGCU 2, DTGCU2, FERM1_HUMAN, Fermitin family homolog 1, Fermt1, FLJ20116, FLJ23423, KIND 1, KIND1, Kinderlin, Kindlerin, Kindlin 1, Kindlin syndrome protein, Kindlin-1, Kindlin1, Unc 112 related protein 1, Unc-112-related protein 1, Unc112 related protein, UNC112A, URP 1, URP1.

Background: Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

Gen-ID: 55612

UniProt: Q9BQL6