Centaurin beta 2 Antikörper (AA 101-200) (Alexa Fluor 350)

Produktnummer ABIN6976493

Produktdetails anti-Centaurin beta 2 Antikörper (Alexa Fluor 350)

Target: Centaurin beta 2 (ACAP2) (ArfGAP with Coiled-Coil, Ankyrin Repeat and PH Domains 2 (ACAP2))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Centaurin beta 2 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Centaurin beta 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Centaurin beta 2

Target: Centaurin beta 2 (ACAP2) (ArfGAP with Coiled-Coil, Ankyrin Repeat and PH Domains 2 (ACAP2))

Andere Bezeichnung: Centaurin beta 2 (ACAP2 Produkte)

Synonyme: CENTB2 antikoerper, CNT-B2 antikoerper, 4832442G16 antikoerper, 9530039J15Rik antikoerper, Centb2 antikoerper, mKIAA0041 antikoerper, centb2 antikoerper, MGC81056 antikoerper, ACAP2 antikoerper, MGC139548 antikoerper, cenB1A antikoerper, si:dkey-254a11.3 antikoerper, ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 antikoerper, ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 L homeolog antikoerper, ACAP2 antikoerper, Acap2 antikoerper, acap3.L antikoerper, acap2 antikoerper

Hintergrund:

Synonyms: ACAP 2, ACAP2, ACAP2_HUMAN, ANK repeat and PH domain-containing protein 2, Ankyrin repeat, Arf GAP with coiled coil ANK repeat and PH domains 2, ARF GAP with coiled coil, Arf-GAP with coiled-coil, CENT B 2, Centaurin beta2, Centaurin-beta-2, CENTB 2, CENTB2, Cnt b2, Cnt-b2, Cntb2, KIAA0041, Pleckstrin homology domains 2, Similar to yeast ZINC FINGER PROTEIN GCS1.

Background: The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins mainly regulate membrane traffic. ACAP2 is a member of the centaurin GTPase-activating protein (GAP) family, which comprises a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. ACAP1 and ACAP2 are both widely expressed in peripheral, tubular membranes and usually interact with each other in various tissues. GAP activity of both ACAP1 and ACAP2 is dependent upon phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2]. ACAP2 associates with ARF1 and ARF6. Overexpression of ACAP2 blocks the formation of ARF6-dependent protrusions. K1L is a protein required for growth of the Vaccinia Virus that interacts with the ankyrin repeats of ACAP2.

Gen-ID: 23527

UniProt: Q15057