TXN Antikörper

Produktnummer ABIN6945149

Produktdetails anti-TXN Antikörper

Target: TXN (Thioredoxin (TXN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TXN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Human Thioredoxin between 50 to 150 amino acids

Klon: 4C7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu TXN

Target: TXN (Thioredoxin (TXN))

Andere Bezeichnung: Thioredoxin (TXN Produkte)

Synonyme: TRDX antikoerper, TRX antikoerper, TRX1 antikoerper, ADF antikoerper, AW550880 antikoerper, Trx1 antikoerper, Txn antikoerper, trx antikoerper, TXN antikoerper, SCM1.18 antikoerper, trxA3 antikoerper, thioredoxin antikoerper, TR-1 antikoerper, Trx-1 antikoerper, thioredoxin antikoerper, thioredoxin 1 antikoerper, thioredoxin L homeolog antikoerper, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) antikoerper, thioredoxin pseudogene antikoerper, cytosolic thioredoxin Trx1 antikoerper, TXN antikoerper, Txn1 antikoerper, txn.L antikoerper, txn antikoerper, trx antikoerper, SCO0885 antikoerper, PHG25ORF099c antikoerper, LOC100349046 antikoerper, Txn antikoerper, trx1 antikoerper

Hintergrund:

Synonyms: ATL-derived factor, Surface-associated sulphydryl protein, Trx, ADF, SASP, TXN

Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

Gen-ID: 7295

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis