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RNF40 Antikörper

RNF40 Reaktivität: Human, Maus, Ratte WB, IP, IHC (p) Wirt: Kaninchen Monoclonal 8D8 unconjugated
Produktnummer ABIN6944788
  • Target Alle RNF40 Antikörper anzeigen
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    Reaktivität
    • 51
    • 15
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 50
    • 2
    Kaninchen
    Klonalität
    • 50
    • 2
    Monoklonal
    Konjugat
    • 25
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser RNF40 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 23
    • 10
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant protein within human RNF40 aa 200-400.
    Klon
    8D8
    Isotyp
    IgG
    Top Product
    Discover our top product RNF40 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IP(1-2 μg)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    Andere Bezeichnung
    RNF40 (RNF40 Produkte)
    Synonyme
    AI848422 antikoerper, mKIAA0661 antikoerper, BRE1B antikoerper, RBP95 antikoerper, STARING antikoerper, ring finger protein 40 antikoerper, RNF40 antikoerper, Rnf40 antikoerper
    Hintergrund

    Synonyms: E3 ubiquitin-protein ligase BRE1B, BRE1-B, 95 kDa retinoblastoma-associated protein, RBP95, RING finger protein 40, RING-type E3 ubiquitin transferase BRE1B, KIAA0661

    Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.

    Gen-ID
    9810
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