RAS Antikörper
-
- Target Alle RAS Produkte
- RAS
-
Reaktivität
- Human, Ratte, Maus, Zebrafisch (Danio rerio)
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser RAS Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio)
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Human Ras aa 1-100
- Klon
- 11F2
- Isotyp
- IgG
-
anti-RAS (AA 31-43) antibody (HRP)
Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal HRP
anti-RAS (AA 31-43) antibodyReaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-RAS (AA 31-43) antibody (FITC)Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal FITC
anti-RAS (AA 31-43) antibody (Alkaline Phosphatase (AP))Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal Alkaline Phosphatase (AP)
anti-RAS (AA 31-43) antibody (APC)Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal APC
anti-RAS (AA 31-43) antibody (Atto 488)Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal Atto 488
anti-RAS (AA 31-43) antibody (Atto 594)Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal Atto 594
anti-RAS (AA 31-43) antibody (Atto 390)Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal Atto 390
anti-RAS (AA 1-190) antibodyReaktivität: Human, Ratte, Maus, Huhn, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 18-Ras unconjugated
anti-RAS antibodyReaktivität: Human, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
-
WB 1:300-5000
FCM 1:20-100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
-
- Target
- RAS
- Abstract
- RAS Produkte
- Synonyme
- asr antikoerper, resistance to audiogenic seizures antikoerper, ras antikoerper
- Hintergrund
-
Synonyms: GTPase Nras, GTPase Hras, GTPase Kras, NRAS, HRAS, KRAS
Background: Ras superfamily is a protein superfamily of small GTPases, which are all related, to a degree, to the Ras protein subfamily (the key human members of which are KRAS, NRAS, and HRAS). Receptor tyrosine kinases and G protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, research studies have shown that in 30 % of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp12 (G12D), which prevents Ras inactivation, possibly by increasing the overall rigidity of the protein. This antibody is predicted to react with H-Ras, N-Ras and K-Ras.
- UniProt
- P01111, P01112, P01116
-
