DDX6 Antikörper

Produktnummer ABIN6942821

Produktdetails anti-DDX6 Antikörper

Target: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser DDX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within human DDX6 aa 100-300

Klon: 15C2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DDX6

Target: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Andere Bezeichnung: DDX6 (DDX6 Produkte)

Synonyme: si:ch211-147p17.1 antikoerper, P54H antikoerper, Xp54 antikoerper, hlr2 antikoerper, me31b antikoerper, p54 antikoerper, rck antikoerper, HLR2 antikoerper, P54 antikoerper, RCK antikoerper, p54h antikoerper, RGD1564560 antikoerper, 1110001P04Rik antikoerper, E230023J21Rik antikoerper, mRCK/P54 antikoerper, DEAD-box helicase 6 antikoerper, DEAD (Asp-Glu-Ala-Asp) box helicase 6 antikoerper, DEAD-box helicase 6 L homeolog antikoerper, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 antikoerper, DDX6 antikoerper, ddx6 antikoerper, ddx6.L antikoerper, Ddx6 antikoerper

Hintergrund:

Synonyms: Probable ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK.

Background: RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell.

Gen-ID: 1656

UniProt: P26196

Pathways: Ribonucleoprotein Complex Subunit Organization