CRMP1 Antikörper

Produktnummer ABIN6942686

Produktdetails anti-CRMP1 Antikörper

Target: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CRMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within human CRMP1 aa 400 to the C-terminus

Klon: 6C5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CRMP1

Target: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Andere Bezeichnung: CRMP1 (CRMP1 Produkte)

Synonyme: CRMP1 antikoerper, crmp1 antikoerper, MGC145930 antikoerper, CRMP 1 antikoerper, CRMP-1 antikoerper, PCRMP 1 antikoerper, PCRMP-1 antikoerper, PCRMP1 antikoerper, PfCRMP-1 antikoerper, DPYSL1 antikoerper, DRP-1 antikoerper, DRP1 antikoerper, ULIP-3 antikoerper, Dpysl1 antikoerper, Ulip3 antikoerper, CRMP1B antikoerper, collapsin response mediator protein 1 antikoerper, dihydropyrimidinase-related protein 1 antikoerper, cysteine repeat modular protein 1, putative antikoerper, collapsin response mediator protein 1 L homeolog antikoerper, CRMP1 antikoerper, crmp1 antikoerper, LOC100350067 antikoerper, PfCRMP1 antikoerper, Crmp1 antikoerper, crmp1.L antikoerper

Hintergrund:

Synonyms: Dihydropyrimidinase-related protein 1, Collapsin response mediator protein 1, Unc-33-like phosphoprotein 3, CRMP-1, ULIP-3, CRMP1, DPYSL1, ULIP3.

Background: Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-1 is also involved in cancer invasion and metastasis. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. CRMP-1 plays a role in axon guidance, invasive growth and cell migration. CRMP-1 may participate in cytokinesis.

Gen-ID: 1400

UniProt: Q14194