ATP6V1G2 Antikörper (AA 51-118) (Alexa Fluor 647)

Produktnummer ABIN6942185

Produktdetails anti-ATP6V1G2 Antikörper (Alexa Fluor 647)

Target: ATP6V1G2 (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G2 (ATP6V1G2))

Bindungsspezifität: AA 51-118

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1G2 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP6V1G2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ATP6V1G2

Target: ATP6V1G2 (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G2 (ATP6V1G2))

Andere Bezeichnung: ATP6V1G2 (ATP6V1G2 Produkte)

Synonyme: ATP6G antikoerper, ATP6V1G1 antikoerper, ATP6G2 antikoerper, NG38 antikoerper, VMA10 antikoerper, ATP6G1 antikoerper, 1500002D01Rik antikoerper, Atp6g2 antikoerper, VAG2 antikoerper, ATPase H+ transporting V1 subunit G2 antikoerper, ATPase, H+ transporting, lysosomal V1 subunit G2 antikoerper, ATP6V1G2 antikoerper, Atp6v1g2 antikoerper

Hintergrund:

Synonyms: ATP6G, ATP6G2, ATPase H+ transporting lysosomal (vacuolar proton pump) subunit G, ATPase H+ transporting lysosomal 13 kDa V1 subunit G2, H(+) transporting two sector ATPase subunit G2, NG 38, NG38, V ATPase 13 kDa subunit 2, V ATPase G subunit 2, V ATPase subunit G 2, Vacuolar ATP synthase subunit G 2, Vacuolar proton pump G subunit 2, Vacuolar proton pump subunit G 2, VMA 10, VMA10.

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene. [provided by RefSeq, Feb 2011]

Gen-ID: 534

UniProt: O95670

Pathways: Transition Metal Ion Homeostasis, Proton Transport