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Insulin Antikörper

INS Reaktivität: Human, Schwein, Maus, Rind (Kuh), Kaninchen IHC, IHC (p), ISt, StM Wirt: Maus Monoclonal IRDN-805 unconjugated
Produktnummer ABIN6939795
  • Target Alle Insulin (INS) Antikörper anzeigen
    Insulin (INS)
    Reaktivität
    • 189
    • 105
    • 90
    • 75
    • 70
    • 39
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Schwein, Maus, Rind (Kuh), Kaninchen
    Wirt
    • 136
    • 86
    • 13
    • 2
    • 1
    • 1
    Maus
    Klonalität
    • 143
    • 98
    Monoklonal
    Konjugat
    • 120
    • 20
    • 15
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Dieser Insulin Antikörper ist unkonjugiert
    Applikation
    • 83
    • 74
    • 67
    • 67
    • 65
    • 54
    • 47
    • 39
    • 26
    • 24
    • 21
    • 16
    • 16
    • 11
    • 9
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunostaining (ISt), Staining Methods (StM)
    Spezifität
    Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
    Keine Kreuzreaktivität
    Ratte (Rattus)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant INS protein
    Klon
    IRDN-805
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product INS Primärantikörper
  • Applikationshinweise

    Positive Control: MIA PaCa-2 cells. Pancreas.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(No special pretreatment is required for staining of formalin/paraffin tissues.)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Insulin (INS)
    Andere Bezeichnung
    INS (INS Produkte)
    Synonyme
    IDDM2 antikoerper, ILPR antikoerper, IRDN antikoerper, MODY10 antikoerper, ins1 antikoerper, xins antikoerper, ins1-a antikoerper, Insulin antikoerper, AA986540 antikoerper, Ins-2 antikoerper, InsII antikoerper, Mody antikoerper, Mody4 antikoerper, proinsulin antikoerper, zgc:109842 antikoerper, igf2-A antikoerper, ins antikoerper, ins-a antikoerper, ins-b antikoerper, insulin antikoerper, insulin precursor antikoerper, insulin II antikoerper, preproinsulin antikoerper, insulin L homeolog antikoerper, insulin S homeolog antikoerper, INS antikoerper, INS-IGF2 antikoerper, ins antikoerper, Ins antikoerper, PIN antikoerper, Ins2 antikoerper, ins.L antikoerper, ins.S antikoerper
    Molekulargewicht
    6kDa
    Gen-ID
    3630
    UniProt
    P01308
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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