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Insulin Antikörper

INS Reaktivität: Human ELISA, IHC, WB, IP Wirt: Maus Monoclonal 2D11-H5 unconjugated
Produktnummer ABIN129507
  • Target Alle Insulin (INS) Antikörper anzeigen
    Insulin (INS)
    Reaktivität
    • 189
    • 106
    • 91
    • 76
    • 71
    • 40
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 137
    • 86
    • 13
    • 2
    • 1
    • 1
    Maus
    Klonalität
    • 144
    • 98
    Monoklonal
    Konjugat
    • 121
    • 20
    • 15
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Dieser Insulin Antikörper ist unkonjugiert
    Applikation
    • 82
    • 74
    • 67
    • 67
    • 65
    • 55
    • 47
    • 39
    • 26
    • 23
    • 21
    • 17
    • 16
    • 11
    • 9
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This protein A purified monoclonal antibody was produced by repeated immunizations with purified human insulin coupled to bovine serum albumin (BSA).
    Immunogentype:Native
    Klon
    2D11-H5
    Isotyp
    IgG
    Top Product
    Discover our top product INS Primärantikörper
  • Applikationshinweise
    This antibody is suitable for ELISA, immunohistochemistry, immunoblotting and immunoprecipitation. Insulin has a cytoplasmic localization.  Pancreatic tissue or b-cells from islets of Langerhans can be used as a positive control.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    Insulin (INS)
    Andere Bezeichnung
    Insulin (INS Produkte)
    Synonyme
    IDDM2 antikoerper, ILPR antikoerper, IRDN antikoerper, MODY10 antikoerper, ins1 antikoerper, xins antikoerper, ins1-a antikoerper, Insulin antikoerper, AA986540 antikoerper, Ins-2 antikoerper, InsII antikoerper, Mody antikoerper, Mody4 antikoerper, proinsulin antikoerper, zgc:109842 antikoerper, igf2-A antikoerper, ins antikoerper, ins-a antikoerper, ins-b antikoerper, insulin antikoerper, insulin precursor antikoerper, insulin II antikoerper, preproinsulin antikoerper, insulin L homeolog antikoerper, insulin S homeolog antikoerper, INS antikoerper, INS-IGF2 antikoerper, ins antikoerper, Ins antikoerper, PIN antikoerper, Ins2 antikoerper, ins.L antikoerper, ins.S antikoerper
    Hintergrund
    Recognizes the 51 amino acid (6 kDa) insulin polypeptide composed of A and B chains. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-peptide basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain acids. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.  The main storage site for insulin is the pancreatic islets.  Antibodies to insulin are important as b-cell and tumor (insulinoma) markers).
    Synonyms: ILPR antibody, INS antibody, Insulin A chain antibody, Insulin B chain antibody, Insulin precursor antibody, IRDN antibody, Proinsulin antibody, Proinsulin precursor antibody
    Gen-ID
    3630
    UniProt
    P01308
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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