SEMA4D/CD100 Antikörper
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- Target Alle SEMA4D/CD100 (SEMA4D) Antikörper anzeigen
- SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SEMA4D/CD100 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Spezifität
- Recognizes a homodimeric protein comprised of 50 kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
- Kreuzreaktivität (Details)
- Human, Monkey, Mouse,
- Aufreinigung
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
- Immunogen
- PHA stimulated human peripheral blood lymphocytes
- Klon
- A8
- Isotyp
- IgG1
- Top Product
- Discover our top product SEMA4D Primärantikörper
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- Applikationshinweise
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Positive Control: Daudi, Raji, HUT-78, Kg1a, U937 and human lymphocytes. Human tonsils and lymph nodes.
Known Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Haltbarkeit
- 24 months
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- Target
- SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
- Andere Bezeichnung
- SEMA4D (SEMA4D Produkte)
- Synonyme
- C9orf164 antikoerper, CD100 antikoerper, M-sema-G antikoerper, SEMAJ antikoerper, coll-4 antikoerper, Semacl2 antikoerper, Semaj antikoerper, Semcl2 antikoerper, COLL-4 antikoerper, semaphorin 4D antikoerper, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D antikoerper, Sema4d antikoerper, SEMA4D antikoerper
- Hintergrund
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COLL4, Collapsin4, GR3, M sema G, MSEMA, SEMA4D, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semcl2,CD100 (Semaphorin-4D)
Cellular localisation: Cell surface - Molekulargewicht
- 50kDa (Monomer)
- Gen-ID
- 10507, 494406
- UniProt
- Q92854
- Pathways
- Regulation of Cell Size
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