TRAP1 Antikörper (AA 501-650) (FITC)
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- Target Alle TRAP1 Antikörper anzeigen
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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Bindungsspezifität
- AA 501-650
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRAP1 Antikörper ist konjugiert mit FITC
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HSP75
- Isotyp
- IgG
- Top Product
- Discover our top product TRAP1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1792-1803, (2016) (PubMed).
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TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1792-1803, (2016) (PubMed).
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- Target
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
- Andere Bezeichnung
- Hsp75/Trap1 (TRAP1 Produkte)
- Synonyme
- HSP 75 antikoerper, HSP75 antikoerper, HSP90L antikoerper, TRAP-1 antikoerper, 2410002K23Rik antikoerper, fc85a11 antikoerper, wu:fc85a11 antikoerper, TNF receptor associated protein 1 antikoerper, TNF receptor-associated protein 1 antikoerper, TRAP1 antikoerper, Trap1 antikoerper, trap1 antikoerper
- Hintergrund
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Synonyms: HSP75, HSP 75, HSP90L, TRAP-1, Heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP1
Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
- Gen-ID
- 10131
- UniProt
- Q12931
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