DNMT1 Antikörper (AA 21-120)
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- Target Alle DNMT1 Antikörper anzeigen
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
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Bindungsspezifität
- AA 21-120
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DNMT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody will not recongize isoform 3.
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Sheep,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Dnmt1
- Isotyp
- IgG
- Top Product
- Discover our top product DNMT1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition." in: Oncotarget, (2015) (PubMed).
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Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition." in: Oncotarget, (2015) (PubMed).
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- Target
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
- Andere Bezeichnung
- Dnmt1 (DNMT1 Produkte)
- Synonyme
- cb1075 antikoerper, cb983 antikoerper, dmnt1 antikoerper, fb05h01 antikoerper, mta antikoerper, wu:fb05h01 antikoerper, ADCADN antikoerper, AIM antikoerper, CXXC9 antikoerper, DNMT antikoerper, HSN1E antikoerper, MCMT antikoerper, DDM2 antikoerper, DECREASED DNA METHYLATION 2 antikoerper, DMT01 antikoerper, DMT1 antikoerper, DNA METHYLTRANSFERASE antikoerper, DNA METHYLTRANSFERASE 01 antikoerper, DNA METHYLTRANSFERASE 1 antikoerper, MET2 antikoerper, METHYLTRANSFERASE 2 antikoerper, METHYLTRANSFERASE I antikoerper, METI antikoerper, methyltransferase 1 antikoerper, Cxxc9 antikoerper, Dnmt antikoerper, Dnmt1o antikoerper, MTase antikoerper, Met-1 antikoerper, Met1 antikoerper, MommeD2 antikoerper, m.MmuI antikoerper, DNA methyltransferase 1 antikoerper, DNA (cytosine-5-)-methyltransferase 1 antikoerper, methyltransferase 1 antikoerper, DNA methyltransferase (cytosine-5) 1 antikoerper, DNMT1 antikoerper, dnmt1 antikoerper, Dnmt1 antikoerper, MET1 antikoerper
- Hintergrund
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Synonyms: AIM, DNMT, MCMT, CXXC9, HSN1E, ADCADN, DNA (cytosine-5)-methyltransferase 1, Dnmt1, CXXC-type zinc finger protein 9, DNA methyltransferase HsaI, DNA MTase HsaI, M.HsaI
Background: Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9.
- Gen-ID
- 1786
- UniProt
- P26358
- Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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