Kv2.1/KCNB1 Antikörper (C-Term)
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- Target Alle Kv2.1/KCNB1 (KCNB1) Antikörper anzeigen
- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Kv2.1/KCNB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- Anti-Kv2.1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv2.1 from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. No cross reactivity to rat Kv2.2. Cross-reactivity with Kv2.1 from other sources has not been determined. Ion Channels research.
- Immunogen
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Immunogen: Kv2.1 Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to the cytoplasmic C-terminus region of rat KV2.1.
Immunogen Type: Peptide
- Klon
- S89-34
- Isotyp
- IgG1
- Top Product
- Discover our top product KCNB1 Primärantikörper
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- Applikationshinweise
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-Kv2.1 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~105-125 kDa on specific lysates (varies with cell background due to phosphorylation). Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: User Optimized
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- Lagerung
- RT,4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Target
- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
- Andere Bezeichnung
- Kv2.1 (KCNB1 Produkte)
- Synonyme
- KCNB1 antikoerper, Kcnb1 antikoerper, Kcr1-1 antikoerper, Kv2.1 antikoerper, Shab antikoerper, DRK1PC antikoerper, DRK1 antikoerper, KV2.1 antikoerper, h-DRK1 antikoerper, potassium voltage-gated channel subfamily B member 1 antikoerper, potassium voltage-gated channel, Shab-related subfamily, member 1 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 1 antikoerper, potassium voltage gated channel, Shab-related subfamily, member 1 antikoerper, KCNB1 antikoerper, kcnb1 antikoerper, LOC100541632 antikoerper, Kcnb1 antikoerper
- Hintergrund
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Synonyms: Shab, Kv2.1, DRK1PC, Kcr1-1, Kcnb1, Potassium voltage-gated channel subfamily B member 1, Delayed rectifier potassium channel 1, DRK1, Voltage-gated potassium channel subunit Kv2.1
Background: Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alpha subunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia.
Gene Name: Kcnb1
- Gen-ID
- 25736
- NCBI Accession
- NP_037318
- UniProt
- P15387
- Pathways
- Synaptic Membrane
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