SETD8 Antikörper (C-Term, N-Term)

Produktnummer ABIN6655982

Produktdetails anti-SETD8 Antikörper

Target: SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Bindungsspezifität: C-Term, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETD8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus

Kreuzreaktivität (Details): Cross reactivity with SETD8 from species other than human and mouse not tested.

Aufreinigung: Anti-SETD8 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Immunogen:

Immunogen: Anti-SETD8 Antibody was produced in rabbits by repeated immunizations of the full length human SETD8 protein containing a Flag-tagged N-terminus and a His-tagged C terminus.

Immunogen Type: Recombinant Protein

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-SETD8 Antibody is suitable for Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 40 kDa in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

0.01 % (w/v) Sodium Azide

Stabilizer: None

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu SETD8

Target: SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Andere Bezeichnung: SETD8 (SETD8 Produkte)

Synonyme: KMT5A antikoerper, PR-Set7 antikoerper, SET07 antikoerper, SET8 antikoerper, 2410195B05Rik antikoerper, AA617402 antikoerper, AW536475 antikoerper, PR-SET7 antikoerper, setd8b antikoerper, wu:fc23f12 antikoerper, zgc:171649 antikoerper, Pr-set7 antikoerper, RGD1305893 antikoerper, Setd8 antikoerper, kmt5a antikoerper, kmt5a-a antikoerper, setd8 antikoerper, setd8-a antikoerper, set8a antikoerper, setd8a antikoerper, wu:fj33f02 antikoerper, zgc:153719 antikoerper, lysine methyltransferase 5A antikoerper, lysine methyltransferase 5Ab antikoerper, lysine methyltransferase 5A S homeolog antikoerper, lysine methyltransferase 5Aa antikoerper, KMT5A antikoerper, Kmt5a antikoerper, kmt5ab antikoerper, kmt5a.S antikoerper, kmt5aa antikoerper

Hintergrund:

Synonyms: N-lysine methyltransferase SETD8, H4-K20-HMTase SETD8, Histone-lysine N-methyltransferse SETD8, Lysine N-methyltransferase 5A, PR/SET domain-containing protein 07, SET domain-containing protein 8, PR-Set7, PR/SET07

Background: SETD8 is a histone methyl transferase that specifically monomethylates 'Lys-20' of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression and is enriched during mitosis. SETD8 may also play a role in maintaining silet chromatin by preventing the acetylation of the H4 tail. Anti-SETD8 Antibody is ideal for research in Gene Expression, Epigenetics and Chromatin Remodeling.

Gene Name: SETD8

Gen-ID: 387893

NCBI Accession: NP_065115

UniProt: Q9NQR1