COBRA1 Antikörper (AA 1-252)

Produktnummer ABIN6654201

Produktdetails anti-COBRA1 Antikörper

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Bindungsspezifität: AA 1-252

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COBRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: Human COBRA1 recombinant protein (amino acids M1-E252) was used as the immunogen for the COBRA1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the COBRA1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the COBRA1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu COBRA1

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Andere Bezeichnung: COBRA1 (COBRA1 Produkte)

Synonyme: LOC100219583 antikoerper, COBRA1 antikoerper, NELF-B antikoerper, bZ1O1.4 antikoerper, cobra1 antikoerper, cobra2 antikoerper, fe01e12 antikoerper, wu:fe01e12 antikoerper, zgc:55628 antikoerper, MGC131073 antikoerper, Cobra1 antikoerper, RGD1307832 antikoerper, A730008L03Rik antikoerper, AB041607 antikoerper, AI663983 antikoerper, Nelf-b antikoerper, cofactor of BRCA1 antikoerper, negative elongation factor complex member B antikoerper, negative elongation factor complex member B L homeolog antikoerper, LOC100219583 antikoerper, NELFB antikoerper, nelfb antikoerper, nelfb.L antikoerper, Nelfb antikoerper

Hintergrund: Cofactor of BRCA1, also known as COBRA1, is a human gene that encodes NELF-B. NELF-B is a subunit of negative elongation factor (NELF), which also includes NELF-A (WHSC2), either NELF-C or NELF-D (TH1L), and NELF-E (RDBP). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1) and SPT5 (SUPT5H), to cause transcriptional pausing of RNA polymerase II. COBRA1 was initially identified in a yeast two-hybrid screen using the BRCT1 domain of BRCA1 as bait.

UniProt: Q8WX92