Grancalcin Antikörper (AA 42-217)

Produktnummer ABIN6654161

Produktdetails anti-Grancalcin Antikörper

Target: Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Bindungsspezifität: AA 42-217

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Grancalcin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids A42-I217 from the human protein were used as the immunogen for the Grancalcin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Grancalcin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Grancalcin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Grancalcin

Target: Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Andere Bezeichnung: Grancalcin / GCA (GCA Produkte)

Synonyme: Grancalcin antikoerper, 5133401E04Rik antikoerper, AI573844 antikoerper, GCL antikoerper, zgc:92027 antikoerper, grancalcin antikoerper, Grancalcin antikoerper, zgc:92027 antikoerper, GCA antikoerper, gran antikoerper, LOC100280890 antikoerper, Gca antikoerper

Hintergrund: Grancalcin is a protein that in humans is encoded by the GCA gene. This gene is mapped to 2q24.2. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction, with magnesium alone, it partitions with the granule fraction, and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

UniProt: P28676