TLN1 Antikörper

Produktnummer ABIN6654085

Produktdetails anti-TLN1 Antikörper

Target: TLN1 (Talin 1 (TLN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids QQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQ were used as the immunogen for the Talin 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Talin 1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Talin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu TLN1

Target: TLN1 (Talin 1 (TLN1))

Andere Bezeichnung: Talin 1 (TLN1 Produkte)

Synonyme: ILWEQ antikoerper, TLN antikoerper, Tln antikoerper, sb:cb854 antikoerper, wu:fb05c02 antikoerper, TLN1 antikoerper, talin-1 antikoerper, tln antikoerper, talin 1 antikoerper, talin 1 L homeolog antikoerper, Talin 1 antikoerper, talin-1 antikoerper, TLN1 antikoerper, Tln1 antikoerper, tln1 antikoerper, tln1.L antikoerper, Bm1_56490 antikoerper, LOC100380665 antikoerper

Hintergrund: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location