TAX1BP3 Antikörper
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- Target Alle TAX1BP3 Antikörper anzeigen
- TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TAX1BP3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human TAX1BP3
- Isotyp
- IgG
- Top Product
- Discover our top product TAX1BP3 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))
- Andere Bezeichnung
- TAX1BP3 (TAX1BP3 Produkte)
- Synonyme
- TIP-1 antikoerper, 1300011C24Rik antikoerper, RP23-263M10.10 antikoerper, tax1bp3 antikoerper, wu:fb37e03 antikoerper, wu:fc23g08 antikoerper, zgc:55513 antikoerper, Tax1 binding protein 3 antikoerper, Tax1 (human T cell leukemia virus type I) binding protein 3 antikoerper, Tax1 (human T-cell leukemia virus type I) binding protein 3 S homeolog antikoerper, Tax1 (human T-cell leukemia virus type I) binding protein 3 antikoerper, TAX1BP3 antikoerper, Tax1bp3 antikoerper, tax1bp3.S antikoerper, tax1bp3 antikoerper
- Hintergrund
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Synonyms: Glutaminase interacting protein 3,Glutaminase-interacting protein 3,Tax interaction protein 1,Tax1 (human T cell leukemia virus type I) binding protein 3,Tax1 binding protein 3,Tax1-binding protein 3,Tax1bp3,TIP 1,TIP-1,TIP1,TX1B3
Background: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways, for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molekulargewicht
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Observed_MW: 14kDa
Calculated_MW: 13kDa
- Gen-ID
- 30851
- UniProt
- O14907
- Pathways
- Monocarboxylic Acid Catabolic Process
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