TAX1BP3 Antikörper

Produktnummer ABIN6571899

Produktdetails anti-TAX1BP3 Antikörper

Target: TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAX1BP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human TAX1BP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TAX1BP3

Target: TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))

Andere Bezeichnung: TAX1BP3 (TAX1BP3 Produkte)

Synonyme: TIP-1 antikoerper, 1300011C24Rik antikoerper, RP23-263M10.10 antikoerper, tax1bp3 antikoerper, wu:fb37e03 antikoerper, wu:fc23g08 antikoerper, zgc:55513 antikoerper, Tax1 binding protein 3 antikoerper, Tax1 (human T cell leukemia virus type I) binding protein 3 antikoerper, Tax1 (human T-cell leukemia virus type I) binding protein 3 S homeolog antikoerper, Tax1 (human T-cell leukemia virus type I) binding protein 3 antikoerper, TAX1BP3 antikoerper, Tax1bp3 antikoerper, tax1bp3.S antikoerper, tax1bp3 antikoerper

Hintergrund:

Synonyms: Glutaminase interacting protein 3,Glutaminase-interacting protein 3,Tax interaction protein 1,Tax1 (human T cell leukemia virus type I) binding protein 3,Tax1 binding protein 3,Tax1-binding protein 3,Tax1bp3,TIP 1,TIP-1,TIP1,TX1B3

Background: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways, for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht:

Observed_MW: 14kDa

Calculated_MW: 13kDa

Gen-ID: 30851

UniProt: O14907

Pathways: Monocarboxylic Acid Catabolic Process