RNF34 Antikörper

Produktnummer ABIN6571814

Produktdetails anti-RNF34 Antikörper

Target: RNF34 (Ring Finger Protein 34 (RNF34))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF34 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human RNF34

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RNF34

Target: RNF34 (Ring Finger Protein 34 (RNF34))

Andere Bezeichnung: RNF34 (RNF34 Produkte)

Synonyme: CARP-1 antikoerper, CARP1 antikoerper, RFI antikoerper, RIF antikoerper, RIFF antikoerper, hRFI antikoerper, rnf34 antikoerper, AW061037 antikoerper, AW536122 antikoerper, BC004042 antikoerper, C88279 antikoerper, Momo antikoerper, fi35g06 antikoerper, wu:fi35g06 antikoerper, zgc:114043 antikoerper, zgc:171755 antikoerper, ring finger protein 34 antikoerper, E3 ubiquitin-protein ligase RNF34 antikoerper, ring finger protein 34a antikoerper, ring finger protein 34b antikoerper, Residual feed intake antikoerper, RNF34 antikoerper, rnf34 antikoerper, Rnf34 antikoerper, rnf34a antikoerper, rnf34b antikoerper, RFI antikoerper

Hintergrund:

Synonyms: CARP 1,CARP-1,CARP1,Caspase regulator CARP1,Caspases-8 and -10-associated RING finger protein 1,E3 ubiquitin-protein ligase RNF34,FYVE-RING finger protein Momo,hRFI,Human RING finger homologous to inhibitor of apoptosis protein,RFI,RIF,RIFF,RING finger protein 34,RING finger protein RIFF,RNF34,RNF34

Background: The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht:

Observed_MW: 42kDa

Calculated_MW: 41kDa

Gen-ID: 80196

UniProt: Q969K3