APITD1 Antikörper

Produktnummer ABIN6571658

Produktdetails anti-APITD1 Antikörper

Target: APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APITD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human APITD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu APITD1

Target: APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

Andere Bezeichnung: APITD1 (APITD1 Produkte)

Synonyme: CENP-S antikoerper, CENPS antikoerper, FAAP16 antikoerper, MHF1 antikoerper, 2610040C18Rik antikoerper, 2810407L01Rik antikoerper, cenps antikoerper, mhf1 antikoerper, APITD1 antikoerper, Apitd1 antikoerper, Mhf1 antikoerper, apitd1 antikoerper, zgc:194319 antikoerper, centromere protein S antikoerper, apoptosis-inducing, TAF9-like domain 1 antikoerper, centromere protein S L homeolog antikoerper, CENPS antikoerper, Cenps antikoerper, cenps.L antikoerper, APITD1 antikoerper, cenps antikoerper

Hintergrund:

Synonyms: APITD1,Apoptosis-inducing TAF9-like domain-containing protein 1,apoptosis-inducing, TAF9-like domain 1,CENP-S,CENPS,CENPS,Centromere protein S,FAAP16,FANCM-interacting histone fold protein 1,Fanconi anemia-associated polypeptide of 16 kDa,MGC32686,MHF 1

Background: This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7.

Molekulargewicht:

Observed_MW: 16kDa

Calculated_MW: 9kDa/15kDa/19kDa

Gen-ID: 100526739

UniProt: Q8N2Z9