SNAP91 Antikörper

Produktnummer ABIN5967842

Produktdetails anti-SNAP91 Antikörper

Target: SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAP91 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CALM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SNAP91

Target: SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))

Andere Bezeichnung: CALM (SNAP91 Produkte)

Synonyme: AP180 antikoerper, CALM antikoerper, Ap180 antikoerper, 91kDa antikoerper, F1-20 antikoerper, mKIAA0656 antikoerper, synaptosome associated protein 91 antikoerper, synaptosomal-associated protein, 91kDa homolog antikoerper, synaptosomal-associated protein 91 antikoerper, SNAP91 antikoerper, LOC100147907 antikoerper, Snap91 antikoerper

Hintergrund:

Synonyms: CALM 1,CALM 2,CALM 3,CALM,CALM,CALM1,CALM2,Calm3,CALML2,calmodulin 1 (phosphorylase kinase,delta),Calmodulin 2 (phosphorylase kinase,delta),Calmodulin 3 (phosphorylase kinase,delta),Calmodulin,CaM,CAM I,CAM1,CAM2,CAM3,CAMB,CAMC,CAMI,CAMII,CPVT4,DD132,FLJ99410,LP7057 protein,PHKD,PHKD2,PHKD3,phosphorylase kinase delta,phosphorylase kinase,delta subunit

Background: This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: 15kDa

Calculated_MW: 17kDa

Gen-ID: 801

UniProt: P62158