ABCC12
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12))
Reaktivität
Maus
Wirt
Kaninchen
Klonalität
Polyklonal
Konjugat
Dieser ABCC12 Antikörper ist unkonjugiert
Applikation
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Klon
RB32878
Bindungsspezifität
AA 723-752
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the Central region of human ABCC12.
ABCC12
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 680
Applikationshinweise
WB: 1:2000. IHC-P: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
ABCC12
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12))
Andere Bezeichnung
ABCC12
Hintergrund
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.