AKR1C4 Antikörper

Produktnummer ABIN5962857

Produktdetails anti-AKR1C4 Antikörper

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human AKR1C4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu AKR1C4

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Andere Bezeichnung: AKR1C4 (AKR1C4 Produkte)

Synonyme: 3-alpha-HSD antikoerper, C11 antikoerper, CDR antikoerper, CHDR antikoerper, DD-4 antikoerper, DD4 antikoerper, HAKRA antikoerper, aldo-keto reductase family 1 member C4 antikoerper, AKR1C4 antikoerper

Hintergrund:

Synonyms: 3 alpha HSD1,3-alpha-HSD1,3-alpha-hydroxysteroid dehydrogenase type I,AK1C4,AKR1C4,Aldo keto reductase family 1 member C4,Aldo-keto reductase family 1 member C4,CDR,Chlordecone reductase,DD-4,DD4,Dihydrodiol dehydrogenase 4,HAKRA

Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Molekulargewicht:

Observed_MW: 37kDa

Calculated_MW: 37kDa

Gen-ID: 1109

UniProt: P17516

Pathways: Steroid Hormone Biosynthesis