PSMB8 Antikörper
-
- Target Alle PSMB8 Antikörper anzeigen
- PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PSMB8 Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PSMB8 (NP_004150.1).
- Isotyp
- IgG
- Top Product
- Discover our top product PSMB8 Primärantikörper
-
-
- Applikationshinweise
- IHC 1:50-1:200 IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
- Andere Bezeichnung
- PSMB8 (PSMB8 Produkte)
- Synonyme
- ALDD antikoerper, D6S216 antikoerper, D6S216E antikoerper, JMP antikoerper, LMP7 antikoerper, NKJO antikoerper, PSMB5i antikoerper, RING10 antikoerper, ATP6V0D2 antikoerper, lmp7 antikoerper, prosome antikoerper, macropain antikoerper, Lmp-7 antikoerper, Lmp7 antikoerper, Ring10 antikoerper, proteasome subunit beta 8 antikoerper, proteasome subunit beta 8A antikoerper, proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) antikoerper, PSMB8 antikoerper, psmb8a antikoerper, Psmb8 antikoerper
- Hintergrund
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified, both isoforms are processed to yield the same mature subunit.
- Molekulargewicht
-
Observed_MW: 23-28kDa
Calculated_MW: 29kDa/30kDa
- Gen-ID
- 5696
- UniProt
- P28062
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
-