MECOM Antikörper

Produktnummer ABIN6570039

Produktdetails anti-MECOM Antikörper

Target: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MECOM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human MECOM

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MECOM

Target: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Andere Bezeichnung: MECOM (MECOM Produkte)

Synonyme: AML1-EVI-1 antikoerper, EVI1 antikoerper, MDS1 antikoerper, MDS1-EVI1 antikoerper, PRDM3 antikoerper, D630039M04Rik antikoerper, Evi-1 antikoerper, Evi1 antikoerper, Jbo antikoerper, Mds antikoerper, Mds1 antikoerper, Mds1-Evi1 antikoerper, Prdm3 antikoerper, Znfpr1b1 antikoerper, evi1 antikoerper, im:7140716 antikoerper, prdm3 antikoerper, evi-1 antikoerper, mecom antikoerper, mecom-a antikoerper, mecom-b antikoerper, xEvi-1 antikoerper, evi1-B antikoerper, MDS1 and EVI1 complex locus antikoerper, MDS1 and EVI1 complex locus L homeolog antikoerper, MDS1 and EVI1 complex locus S homeolog antikoerper, MECOM antikoerper, Mecom antikoerper, mecom antikoerper, mecom.L antikoerper, mecom.S antikoerper

Hintergrund:

Synonyms: MDS1 And EVI1 Complex Locus,Ecotropic Virus Integration Site 1 Protein Homolog,Myelodysplasia Syndrome-Associated Protein 1,PR Domain 3,EVI1,MDS1,MDS1 And EVI1 Complex Locus Protein EVI1,MDS1 And EVI1 Complex Locus Protein MDS1,Ecotropic Viral Integration Site 1,Myelodysplasia Syndrome 1 Protein,Myelodysplasia Syndrome 1,AML1-EVI-1 Fusion Protein,Zinc Finger Protein Evi1,Oncogene EVI1,AML1-EVI-1,MDS1-EVI1,RUSAT2,KMT8E,PRDM3,EVI-1

Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 22kDa

Calculated_MW: 18kDa/117kDa/118kDa/125kDa/139kDa

Gen-ID: 2122

UniProt: Q03112, Q13465