CDC45 Antikörper
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- Target Alle CDC45 Antikörper anzeigen
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDC45 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CDC45 (NP_003495.1).
- Isotyp
- IgG
- Top Product
- Discover our top product CDC45 Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
- Andere Bezeichnung
- CDC45 (CDC45 Produkte)
- Synonyme
- cdc45l antikoerper, cdc45l2 antikoerper, porc-pi-1 antikoerper, CDC45L antikoerper, CDC45L2 antikoerper, PORC-PI-1 antikoerper, Cdc45l antikoerper, cell division cycle 45 antikoerper, cell division cycle 45 S homeolog antikoerper, cell division cycle 45 L homeolog antikoerper, cdc45 antikoerper, CDC45 antikoerper, cdc45.S antikoerper, Cdc45 antikoerper, cdc45.L antikoerper
- Hintergrund
- The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
- Molekulargewicht
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Observed_MW: 60kDa
Calculated_MW: 60kDa/65kDa/68kDa
- Gen-ID
- 8318
- UniProt
- O75419
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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