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Uromodulin Antikörper

UMOD Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5964310
  • Target Alle Uromodulin (UMOD) Antikörper anzeigen
    Uromodulin (UMOD)
    Reaktivität
    • 55
    • 24
    • 21
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 45
    • 12
    • 6
    • 2
    Kaninchen
    Klonalität
    • 55
    • 10
    Polyklonal
    Konjugat
    • 33
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Uromodulin Antikörper ist unkonjugiert
    Applikation
    • 54
    • 26
    • 22
    • 16
    • 14
    • 13
    • 13
    • 11
    • 9
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human UMOD
    Isotyp
    IgG
    Top Product
    Discover our top product UMOD Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Uromodulin (UMOD)
    Andere Bezeichnung
    UMOD (UMOD Produkte)
    Synonyme
    ADMCKD2 antikoerper, FJHN antikoerper, HNFJ antikoerper, HNFJ1 antikoerper, MCKD2 antikoerper, THGP antikoerper, THP antikoerper, urehr4 antikoerper, uromodulin antikoerper, UMOD antikoerper, Umod antikoerper
    Hintergrund

    Synonyms: ADMCKD2,FJHN,HNFJ,HNFJ1,MCKD2,medullary cystic kidney disease 2 (autosomal dominant),Tamm Horsfall glycoprotein,Tamm Horsfall urinary glycoprotein,Tamm-Horsfall urinary glycoprotein,THGP,THP,Umod,Urehd1,urehr4,UROM,uromodulin (uromucoid,Tamm-Horsfall glycoprotein),Uromodulin,Uromodulin,secreted form

    Background: The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.

    Molekulargewicht

    Observed_MW: 70kDa

    Calculated_MW: 55kDa/66kDa/67kDa/69kDa/73kDa

    Gen-ID
    7369
    UniProt
    P07911
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