Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9) Antikörper

Details zu Produkt Nr. ABIN6568889
Target
Reaktivität
Human, Maus
66
30
29
7
2
2
2
2
1
1
1
1
1
1
1
Wirt
Kaninchen
56
11
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
5
5
3
3
3
3
3
3
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
54
33
29
16
14
10
3
3
2
2
2
2
1
Optionen
Immunogen Recombinant protein of human PSMB9
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PSMB9 (PSMB9 Antibody Abstract)
Hintergrund

Synonyms: Beta1i,Large multifunctional peptidase 2,Large multifunctional protease 2,LMP 2,LMP2,Low molecular mass protein 2,Macropain chain 7,MGC70470,Multicatalytic endopeptidase complex chain 7,OTTHUMP00000062982,Proteasome (prosome macropain) subunit beta type 9,proteasome (prosome,macropain) subunit,beta type,9 (large multifunctional peptidase 2),Proteasome beta 9 subunit,Proteasome catalytic subunit 1i,Proteasome chain 7,Proteasome related gene 2,Proteasome subunit beta 6i,Proteasome subunit beta type 9,Proteasome subunit beta type-9,Proteasome subunit beta-1i,PSB9,PSMB 9,PSMB6i,PSMB9,Really interesting new gene 12 protein,RING 12,RING12,RING12 protein

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.

Molekulargewicht

Observed_MW: 22kDa

Calculated_MW: 22kDa/23kDa

Gen-ID 5698
UniProt P28065
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Applikations-hinweise WB 1:500 - 1:2000 IF 1:10 - 1:100
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9) antibody (ABIN6568889) Immunofluorescence analysis of MCF-7 cells using PSMB9 antibody.
Image no. 2 for anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9) antibody (ABIN6568889) Western blot analysis of extracts of various cell lines, using PSMB9 antibody.