ORC1 Antikörper
-
- Target Alle ORC1 (ORC1L) Antikörper anzeigen
- ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ORC1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human ORC1
- Isotyp
- IgG
- Top Product
- Discover our top product ORC1L Primärantikörper
-
-
- Applikationshinweise
- WB 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))
- Andere Bezeichnung
- ORC1 (ORC1L Produkte)
- Synonyme
- CG10667 antikoerper, DmORC1 antikoerper, DmOrc1 antikoerper, DmOrc1p antikoerper, Dmel\\CG10667 antikoerper, ORC antikoerper, ORC1 antikoerper, dORC1 antikoerper, orc1 antikoerper, rDmORC antikoerper, ORC1L antikoerper, HSORC1 antikoerper, PARC1 antikoerper, orc1l antikoerper, xorc1 antikoerper, AA545195 antikoerper, MmORC1 antikoerper, Orc1l antikoerper, Origin recognition complex subunit 1 antikoerper, origin recognition complex subunit 1 antikoerper, origin recognition complex subunit 1 L homeolog antikoerper, origin recognition complex, subunit 1 antikoerper, Orc1 antikoerper, ORC1 antikoerper, orc1.L antikoerper
- Hintergrund
-
Synonyms: HSORC1,MmORC1,orc1,ORC1,ORC1L,Origin Recognition Complex 1,Origin recognition complex subunit 1 (yeast homolog) like,Origin recognition complex subunit 1,Origin recognition complex subunit 1 homolog,Origin recognition complex subunit 1 like (S. cerevisia,Origin recognition complex subunit 1 like,Origin recognition complex subunit 1 S. cerevisiae homolog like ,Origin recognition complex,subunit 1 like (yeast),PARC1,Replication control protein 1
Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
-
Observed_MW: 90kDa
Calculated_MW: 97kDa
- Gen-ID
- 4998
- UniProt
- Q13415
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
-