Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 (PSMA6) Antikörper

Details zu Produkt Nr. ABIN6568027
Target
Reaktivität
Human, Affe, Maus, Ratte
45
32
31
6
6
5
5
4
4
4
4
2
2
2
1
1
1
1
1
Wirt
Kaninchen
37
8
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
33
14
13
11
10
6
4
3
3
2
1
1
Optionen
Immunogen Recombinant protein of human PSMA6
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PSMA6 (PSMA6 Antibody Abstract)
Hintergrund

Synonyms: 27 kDa prosomal protein,IOTA,Macropain iota chain,Macropain subunit iota,MGC22756,MGC2333,MGC23846,Multicatalytic endopeptidase complex iota chain,p27K,PROS 27,PROS-27,PROS27,Prosomal P27K protein,Proteasome (prosome macropain) subunit alpha type 6,Proteasome iota chain,Proteasome subunit alpha type 6,Proteasome subunit alpha type-6,Proteasome subunit iota,PSA6,PSMA 6,PSMA6

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

Molekulargewicht

Observed_MW: 30kDa

Calculated_MW: 18kDa/25kDa/27kDa

Gen-ID 5687
UniProt P60900
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 (PSMA6) antibody (ABIN6568027) Western blot analysis of extracts of various cell lines, using PSMA6 antibody.
Image no. 2 for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 (PSMA6) antibody (ABIN6568027) Immunohistochemistry of paraffin-embedded human lung cancer using PSMA6 antibody.
Image no. 3 for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 6 (PSMA6) antibody (ABIN6568027) Immunofluorescence analysis of MCF-7 cells using PSMA6 antibody.