STARD5 Antikörper (N-Term)

Produktnummer ABIN656750

Produktdetails anti-STARD5 Antikörper

Target: STARD5 (StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5))

Bindungsspezifität: AA 26-55, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STARD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STARD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human STARD5.

Klon: RB32496

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: STARD5 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu STARD5

Target: STARD5 (StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5))

Andere Bezeichnung: STARD5 (STARD5 Produkte)

Synonyme: STARD5 antikoerper, MGC131265 antikoerper, DKFZp469N2125 antikoerper, 2310058G22Rik antikoerper, AI607880 antikoerper, D7Ertd152e antikoerper, RGD1561783 antikoerper, StAR related lipid transfer domain containing 5 antikoerper, StAR related lipid transfer domain containing 5 S homeolog antikoerper, StAR-related lipid transfer (START) domain containing 5 antikoerper, StAR-related lipid transfer domain containing 5 antikoerper, STARD5 antikoerper, stard5.S antikoerper, Stard5 antikoerper

Hintergrund: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 [PubMed 12011452]).

Molekulargewicht: 23794

Gen-ID: 80765

NCBI Accession: NP_871629

UniProt: Q9NSY2

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process