SIPA1 Antikörper

Produktnummer ABIN6567395

Produktdetails anti-SIPA1 Antikörper

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human SIPA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SIPA1

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Andere Bezeichnung: SIPA1 (SIPA1 Produkte)

Synonyme: Spa1 antikoerper, SPA1 antikoerper, signal-induced proliferation-associated 1 antikoerper, Signal peptidase I (leader peptidase I) antikoerper, signal-induced proliferation associated gene 1 antikoerper, SIPA1 antikoerper, sipA1 antikoerper, Sipa1 antikoerper

Hintergrund:

Synonyms: GTPase activating protein Spa 1,GTPase-activating protein Spa-1,MGC102688,MGC17037,p130 SPA-1,p130 SPA1,Signal induced proliferation associated 1,Signal induced proliferation associated gene 1,Signal induced proliferation associated protein 1,Signal-induced proliferation-associated protein 1,SIPA 1,Sipa-1,Sipa1,SIPA1,Spa1

Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Molekulargewicht:

Observed_MW: 130kDa

Calculated_MW: 112kDa

Gen-ID: 6494

UniProt: Q96FS4

Pathways: Response to Water Deprivation