beta Arrestin 1 Antikörper

Produktnummer ABIN5962975

Produktdetails anti-beta Arrestin 1 Antikörper

Target: beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser beta Arrestin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ARRB1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu beta Arrestin 1

Target: beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

Andere Bezeichnung: ARRB1 (ARRB1 Produkte)

Synonyme: arrb1 antikoerper, MGC83787 antikoerper, arb1 antikoerper, arr1 antikoerper, barr1 antikoerper, betaarr1 antikoerper, 1200006I17Rik antikoerper, AW208571 antikoerper, G430100A01Rik antikoerper, ARB1 antikoerper, ARR1 antikoerper, BARRES antikoerper, arrestin beta 1 antikoerper, arrestin, beta 1 antikoerper, arrestin beta 1 L homeolog antikoerper, beta-arrestin 1 antikoerper, putative beta-arrestin 1 antikoerper, ARRB1 antikoerper, arrb1 antikoerper, arrb1.L antikoerper, CpipJ_CPIJ016988 antikoerper, CpipJ_CPIJ017114 antikoerper, Smp_122900 antikoerper, Smp_126080 antikoerper, Smp_176980 antikoerper, Smp_152290 antikoerper, Arrb1 antikoerper

Hintergrund:

Synonyms: ARB1,ARR1,ARRB1,ARRB1,Arrestin 2,Arrestin beta 1,Arrestin beta-1,Beta-arrestin-1

Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

Molekulargewicht:

Observed_MW: 43-54kDa

Calculated_MW: 46kDa/47kDa

Gen-ID: 408

UniProt: P49407

Pathways: Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction