MYSM1 Antikörper (N-Term)

Produktnummer ABIN654474

Produktdetails anti-MYSM1 Antikörper

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Bindungsspezifität: AA 111-139, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYSM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MYSM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human MYSM1.

Klon: RB27661

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MYSM1

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Andere Bezeichnung: MYSM1 (MYSM1 Produkte)

Synonyme: 2A-DUB antikoerper, 2ADUB antikoerper, RP4-592A1.1 antikoerper, C130067A03Rik antikoerper, C530050H10Rik antikoerper, RGD1311787 antikoerper, 2adub antikoerper, Myb like, SWIRM and MPN domains 1 antikoerper, myb-like, SWIRM and MPN domains 1 antikoerper, Myb like, SWIRM and MPN domains 1 L homeolog antikoerper, MYSM1 antikoerper, Mysm1 antikoerper, mysm1.L antikoerper

Hintergrund: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Molekulargewicht: 95032

Gen-ID: 114803

NCBI Accession: NP_001078956

UniProt: Q5VVJ2

Pathways: Chromatin Binding