FBXW12 Antikörper (C-Term)

Produktnummer ABIN654226

Produktdetails anti-FBXW12 Antikörper

Target: FBXW12 (F-Box and WD Repeat Domain Containing 12 (FBXW12))

Bindungsspezifität: AA 291-320, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBXW12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human FBXW12.

Klon: RB27619

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu FBXW12

Target: FBXW12 (F-Box and WD Repeat Domain Containing 12 (FBXW12))

Andere Bezeichnung: FBXW12 (FBXW12 Produkte)

Synonyme: FBW12 antikoerper, FBXO12 antikoerper, FBXO35 antikoerper, RGD1307859 antikoerper, F-box and WD repeat domain containing 12 antikoerper, FBXW12 antikoerper, Fbxw12 antikoerper

Hintergrund: Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

Gen-ID: 285231

NCBI Accession: NP_001153399, NP_001153401, NP_996985

UniProt: Q6X9E4