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LINGO1 Antikörper (C-Term)

LINGO1 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB15362 unconjugated
Produktnummer ABIN651289
  • Target Alle LINGO1 Antikörper anzeigen
    LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
    Bindungsspezifität
    • 15
    • 13
    • 13
    • 10
    • 9
    • 9
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 575-603, C-Term
    Reaktivität
    • 58
    • 34
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 73
    Kaninchen
    Klonalität
    • 73
    Polyklonal
    Konjugat
    • 22
    • 8
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LINGO1 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 43
    • 30
    • 13
    • 13
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    C, Pr
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This LINGO-1(LRRN6A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 amino acids from the C-terminal region of human LINGO-1(LRRN6A).
    Klon
    RB15362
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IHC: 1:50. IHC: 1:125. WB: 1:1000-1:2000. IHC-P: 1:50~100. IHC: 1:250. IHC: 1:125
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Towner, Jensen, Vaillant, Colman, Saunders, Giles, Wren: "Experimental validation of 5 in-silico predicted glioma biomarkers." in: Neuro-oncology, Vol. 15, Issue 12, pp. 1625-34, (2013) (PubMed).

  • Target
    LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
    Andere Bezeichnung
    LINGO-1 (LRRN6A) (LINGO1 Produkte)
    Synonyme
    lern1 antikoerper, lrrn6a antikoerper, unq201 antikoerper, DKFZp459P0736 antikoerper, LERN1 antikoerper, LRRN6A antikoerper, UNQ201 antikoerper, 4930471K13Rik antikoerper, AV148400 antikoerper, LINGO-1 antikoerper, Lrrn6a antikoerper, leucine rich repeat and Ig domain containing 1 antikoerper, LINGO1 antikoerper, lingo1 antikoerper, Lingo1 antikoerper
    Hintergrund
    LINGO-1 is functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. LINGO-1 is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
    Molekulargewicht
    69101
    Gen-ID
    235402
    NCBI Accession
    NP_851419
    UniProt
    Q9D1T0
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