TACI Antikörper

Produktnummer ABIN636608

Produktdetails anti-TACI Antikörper

Target: TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TACI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Aufreinigung: Purified

Immunogen: TACI antibody was raised in goat using highly pure recombinant human TACI as the immunogen.

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu TACI

Target: TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

Andere Bezeichnung: TACI (TNFRSF13B Produkte)

Synonyme: CD267 antikoerper, CVID antikoerper, CVID2 antikoerper, RYZN antikoerper, TACI antikoerper, TNFRSF14B antikoerper, TNFRSF13B antikoerper, 1200009E08Rik antikoerper, Taci antikoerper, TNF receptor superfamily member 13B antikoerper, tumor necrosis factor receptor superfamily, member 13b antikoerper, TNFRSF13B antikoerper, Tnfrsf13b antikoerper

Hintergrund: TACI, a member of the TNF Receptor superfamily, is expressed in the small intestine, spleen, thymus, peripheral blood leukocytes, activated T cells, and resting B cells. TACI binds to both APRIL and BAFF and can stimulate the activation of transcription factors, NF-kappaB, AP-1, and mediates calcineurin dependent activation of NF-AT (nuclear-factor of activated T cells). TACI also plays a key role in the stimulation of B and T cell function. Soluble TACI inhibits APRILstimulated proliferation of primary B-cells by blocking the binding of APRIL to the membrane anchored TACI receptor.

Molekulargewicht: 17.8 kDa (predicted detection band MW)