SH3BP2 Antikörper (Middle Region)
Kurzübersicht für SH3BP2 Antikörper (Middle Region) (ABIN634378)
Target
Alle SH3BP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Spezifität
- SH3 BP2 antibody was raised against the middle region of SH3 P2
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Aufreinigung
- Affinity purified
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Immunogen
- SH3 BP2 antibody was raised using the middle region of SH3 P2 corresponding to a region with amino acids RQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQ
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Applikationshinweise
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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SH3BP2 Blocking Peptide, (ABIN5616123), is also available for use as a blocking control in assays to test for specificity of this SH3BP2 antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SH0 P2 antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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Andere Bezeichnung
- SH3BP2
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Hintergrund
- SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.
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Molekulargewicht
- 62 kDa (MW of target protein)
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Pathways
- T-Zell Rezeptor Signalweg
Target
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