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Manic Fringe Antikörper (Middle Region)

MFNG Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN633860
  • Target Alle Manic Fringe (MFNG) Antikörper anzeigen
    Manic Fringe (MFNG) (MFNG)
    Bindungsspezifität
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 27
    • 26
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 40
    • 4
    • 1
    Kaninchen
    Klonalität
    • 44
    • 1
    Polyklonal
    Konjugat
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Manic Fringe Antikörper ist unkonjugiert
    Applikation
    • 19
    • 14
    • 14
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    MFNG antibody was raised against the middle region of MFNG
    Aufreinigung
    Affinity purified
    Immunogen
    MFNG antibody was raised using the middle region of MFNG corresponding to a region with amino acids MAPWASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETL
    Top Product
    Discover our top product MFNG Primärantikörper
  • Applikationshinweise
    WB: 0.25 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    MFNG Blocking Peptide, catalog no. 33R-5720, is also available for use as a blocking control in assays to test for specificity of this MFNG antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MFNG antibody in PBS
    Konzentration
    Lot specific
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    Manic Fringe (MFNG) (MFNG)
    Andere Bezeichnung
    MFNG (MFNG Produkte)
    Synonyme
    AW546563 antikoerper, MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antikoerper, MFNG antikoerper, Mfng antikoerper
    Hintergrund
    MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
    Molekulargewicht
    36 kDa (MW of target protein)
    Pathways
    Notch Signalweg
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