CYP27A1 Antikörper (Middle Region)

Produktnummer ABIN631030

Produktdetails anti-CYP27A1 Antikörper

Target: CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP27A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: CYP27 A1 antibody was raised against the middle region of CYP27 1

Aufreinigung: Affinity purified

Immunogen: CYP27 A1 antibody was raised using the middle region of CYP27 1 corresponding to a region with amino acids SRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRI

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CYP27A1 Blocking Peptide, catalog no. 33R-8744, is also available for use as a blocking control in assays to test for specificity of this CYP27A1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CYP20 1 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu CYP27A1

Target: CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

Andere Bezeichnung: CYP27A1 (CYP27A1 Produkte)

Synonyme: CP27 antikoerper, CTX antikoerper, CYP27 antikoerper, Cyp27 antikoerper, P450C27 antikoerper, 1300013A03Rik antikoerper, cytochrome P450 family 27 subfamily A member 1 antikoerper, cytochrome P450, family 27, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 27, subfamily A, polypeptide 1 antikoerper, sterol 26-hydroxylase, mitochondrial antikoerper, CYP27A1 antikoerper, Cyp27a1 antikoerper, cyp27a1 antikoerper

Hintergrund: CYP27A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.

Molekulargewicht: 57 kDa (MW of target protein)