FNTA Antikörper (Center)

Produktnummer ABIN6295422

Produktdetails anti-FNTA Antikörper

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Bindungsspezifität: AA 88-118, Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FNTA Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Verwendungszweck: Rabbit Anti-FNTA (Center) Antibody

Immunogen: This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the Central region of human FNTA.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu FNTA

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Andere Bezeichnung: FNTA (FNTA Produkte)

Synonyme: ATFTA antikoerper, FARNESYLTRANSFERASE A antikoerper, FARNESYLTRANSFERASE SUBUNIT A antikoerper, PFT/PGGT-IALPHA antikoerper, PLP antikoerper, PLURIPETALA antikoerper, farnesyltransferase A antikoerper, FPTA antikoerper, PGGT1A antikoerper, PTAR2 antikoerper, PFAS antikoerper, FTA antikoerper, farnesyltransferase A antikoerper, farnesyltransferase, CAAX box, alpha antikoerper, FTA antikoerper, FNTA antikoerper, Fnta antikoerper

Hintergrund:

Target Description: FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

Gene Symbol: FNTA

Gen-ID: 2339

UniProt: P49354

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling