PES1 Antikörper
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- Target Alle PES1 Antikörper anzeigen
- PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PES1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human PES1
- Isotyp
- IgG
- Top Product
- Discover our top product PES1 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000
- Kommentare
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Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells, Levels are abnormally elevated in malignant tumors of astrocytic origin
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
- Andere Bezeichnung
- PES1 (PES1 Produkte)
- Synonyme
- PES antikoerper, pes antikoerper, pes1 antikoerper, pescadillo ribosomal biogenesis factor 1 antikoerper, pescadillo ribosomal biogenesis factor 1 S homeolog antikoerper, Pescadillo antikoerper, PES1 antikoerper, Pes1 antikoerper, pes1.S antikoerper, pesc antikoerper
- Hintergrund
- This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
- Molekulargewicht
- 68.003 kDa
- Gen-ID
- 23481
- UniProt
- O00541
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