RASGRP2 Antikörper

Produktnummer ABIN6293518

Produktdetails anti-RASGRP2 Antikörper

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human RASGRP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000

Kommentare:

Detected in platelets, neutrophils and T lymphocytes (at protein level), Expressed in brain where it is enriched in the striatum, Also expressed in the hematopoietic system, Detected in heart, brain, lung, placenta, liver, skeletal muscle and kidney

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu RASGRP2

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Andere Bezeichnung: RASGRP2 (RASGRP2 Produkte)

Synonyme: CALDAG-GEFI antikoerper, CDC25L antikoerper, xrasgrp2 antikoerper, RASGRP2 antikoerper, Caldaggef1 antikoerper, CalDAG-GEFI antikoerper, rasgrp2 antikoerper, RAS guanyl releasing protein 2 antikoerper, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog antikoerper, RAS, guanyl releasing protein 2 antikoerper, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog antikoerper, RASGRP2 antikoerper, rasgrp2.S antikoerper, Rasgrp2 antikoerper, rasgrp2.L antikoerper

Hintergrund: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

Molekulargewicht: 69.248 kDa

Gen-ID: 10235

UniProt: Q7LDG7

Pathways: T-Zell Rezeptor Signalweg