COQ6 Antikörper

Produktnummer ABIN6293279

Produktdetails anti-COQ6 Antikörper

Target: COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COQ6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human COQ6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Widely expressed

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu COQ6

Target: COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

Andere Bezeichnung: COQ6 (COQ6 Produkte)

Synonyme: CGI10 antikoerper, COQ10D6 antikoerper, 5930427M12Rik antikoerper, AW742344 antikoerper, zgc:153379 antikoerper, coq6 antikoerper, coenzyme Q6, monooxygenase antikoerper, coenzyme Q6 monooxygenase antikoerper, Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial antikoerper, coenzyme Q6 monooxygenase L homeolog antikoerper, COQ6 antikoerper, Coq6 antikoerper, coq-6 antikoerper, coq6 antikoerper, coq6.L antikoerper

Hintergrund: The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 50.87 kDa

Gen-ID: 51004

UniProt: Q9Y2Z9