LRWD1 Antikörper

Produktnummer ABIN6293055

Produktdetails anti-LRWD1 Antikörper

Target: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRWD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human Lrwd1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000

Kommentare:

Testis-specific, Drastically down-regulated in testis from patients with Sertoli cell-only syndrome (SCOS)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu LRWD1

Target: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Andere Bezeichnung: LRWD1 (LRWD1 Produkte)

Synonyme: CENP-33 antikoerper, ORCA antikoerper, 1200011O22Rik antikoerper, AU042569 antikoerper, AW548074 antikoerper, Orca antikoerper, si:dkey-261j4.9 antikoerper, wu:fb78b03 antikoerper, wu:ft31b04 antikoerper, leucine rich repeats and WD repeat domain containing 1 antikoerper, leucine-rich repeats and WD repeat domain containing 1 antikoerper, microRNA 5090 antikoerper, leucine-rich repeats and WD repeat domain containing 1 L homeolog antikoerper, LRWD1 antikoerper, Lrwd1 antikoerper, lrwd1 antikoerper, MIR5090 antikoerper, lrwd1.L antikoerper

Hintergrund: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 70.861 kDa

Gen-ID: 222229

UniProt: Q9UFC0

Pathways: Chromatin Binding